STANDARDIZATION OF THE INDIAN CRUDE DRUG KALMEGH BY HIGH-PRESSURE LIQUID-CHROMATOGRAPHIC DETERMINATION OF ANDROGRAPHOLIDE

被引:54
作者
SHARMA, A [1 ]
LAL, K [1 ]
HANDA, SS [1 ]
机构
[1] PANJAB UNIV,DEPT PHARMACEUT SCI,ICMR,CHANDIGARH 160014,INDIA
关键词
STANDARDIZATION; ANDROGRAPHOLIDE; ANDROGRAPHIS-PANICULATA; KALMEGH; HIGH PRESSURE LIQUID CHROMATOGRAPHY;
D O I
10.1002/pca.2800030308
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The popular hepatoprotective Indian herbal drug Kalmegh (Andrographis paniculata) can be standardized by high pressure liquid chromatographic determination of its major active constituent, andrographolide. The leaves of the herb were found to contain the highest amount (2.39% w/w) of andrographolide and the seeds to contain the lowest. The technique was found to be much more sensitive and simple than the known spectrophotometric method
引用
收藏
页码:129 / 131
页数:3
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