CELL-VOLUME AND HEPATOCELLULAR FUNCTION

被引：27

作者：

HAUSSINGER, D

SCHLIESS, F

机构：

[1] Medizinische Universitätsklinik, Heinrich-Heine-Universität, Düsseldorf

来源：

JOURNAL OF HEPATOLOGY | 1995年 / 22卷 / 01期

关键词：

D O I：

10.1016/0168-8278(95)80266-5

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The hepatocellular hydration state, i.e. liver cell volume, is a dynamic parameter, which changes within minutes in response to alterations in the environmental or hormonal milieu. These changes in cell hydration act as a signal which modifies metabolism and gene expression due to complex alterations in protein phosphorylation. The role of cellular hydration as an important determinant of liver cell function and gene expression may shed a new light not only on liver physiology but also on liver pathophysiology. (C) Journal of Hepatology.

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页码：94 / 100

页数：7

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