学术探索
学术期刊
新闻热点
数据分析
智能评审

STRUCTURE AND EVOLUTION OF THE ACTIN CROSS-LINKING PROTEINS

被引：65
作者：
DUBREUIL, RR
机构：
[1] Biological Laboratories, Harvard University, Cambridge, Massachusetts
来源：
BIOESSAYS | 1991年 / 13卷 / 05期
关键词：
D O I：
10.1002/bies.950130504
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The actin crosslinking proteins exhibit marked diversity in size and shape and crosslink actin filaments in different ways. Amino acid sequence analysis of many of these proteins has provided clues to the origin of their diversity. Spectrin, alpha-actinin, ABP-120, ABP-280, fimbrin, and dystrophin share a homologous sequence segment that is implicated as the common actin binding domain. The remainder of each protein consists of repetitive and non-repetitive sequence segments that have been shuffled and multiplied in evolution to produce a variety of proteins that are related in function and in composition, but that differ significantly in structure.
引用
收藏
页码：219 / 226
页数：8
相关论文
共 68 条
  • [1] PRIMARY STRUCTURE OF CHICKEN SKELETAL-MUSCLE AND FIBROBLAST ALPHA-ACTININS DEDUCED FROM CDNA SEQUENCES
    ARIMURA, C
    SUZUKI, T
    YANAGISAWA, M
    IMAMURA, M
    HAMADA, Y
    MASAKI, T
    [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1988, 177 (03): : 649 - 655
  • [2] BARON MD, 1987, J BIOL CHEM, V262, P17623
  • [3] THE MEMBRANE SKELETON OF HUMAN-ERYTHROCYTES AND ITS IMPLICATIONS FOR MORE COMPLEX CELLS
    BENNETT, V
    [J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1985, 54 : 273 - 304
  • [4] DO GENES-IN-PIECES IMPLY PROTEINS-IN-PIECES
    BLAKE, CCF
    [J]. NATURE, 1978, 273 (5660) : 267 - 267
  • [5] THE STRUCTURE AND FUNCTION OF ALPHA-ACTININ
    BLANCHARD, A
    OHANIAN, V
    CRITCHLEY, D
    [J]. JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 1989, 10 (04) : 280 - 289
  • [6] BRESNICK AR, 1990, J BIOL CHEM, V265, P9236
  • [7] FIMBRIN, A NEW MICROFILAMENT-ASSOCIATED PROTEIN PRESENT IN MICROVILLI AND OTHER CELL-SURFACE STRUCTURES
    BRETSCHER, A
    WEBER, K
    [J]. JOURNAL OF CELL BIOLOGY, 1980, 86 (01) : 335 - 340
  • [8] A DICTYOSTELIUM MUTANT LACKING AN F-ACTIN CROSS-LINKING PROTEIN, THE 120-KD GELATION FACTOR
    BRINK, M
    GERISCH, G
    ISENBERG, G
    NOEGEL, AA
    SEGALL, JE
    WALLRAFF, E
    SCHLEICHER, M
    [J]. JOURNAL OF CELL BIOLOGY, 1990, 111 (04) : 1477 - 1489
  • [9] BRYAN J, 1989, J BIOL CHEM, V264, P13873
  • [10] NON-MUSCLE ALPHA-ACTININS ARE CALCIUM-SENSITIVE ACTIN-BINDING PROTEINS
    BURRIDGE, K
    FERAMISCO, JR
    [J]. NATURE, 1981, 294 (5841) : 565 - 567
1234567