THE B-CELL ANTIGEN RECEPTOR COMPLEX - STRUCTURE AND SIGNAL-TRANSDUCTION

被引:184
作者
PLEIMAN, CM
DAMBROSIO, D
CAMBIER, JC
机构
[1] Christopher M. Pleiman, Daniele D'Ambrosio and John C. Cambier are, the National Jewish Center for Immunology and Respiratory Medicine, Denver, CO 80220
来源
IMMUNOLOGY TODAY | 1994年 / 15卷 / 09期
关键词
D O I
10.1016/0167-5699(94)90267-4
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The specificity of the immune response is determined by the interaction between the B-cell receptor (BCR) and its cogitate structure, antigen. Recent studies have provided considerable insight into the compartmentalization of function within this extremely versatile hetero-oligomeric receptor complex. In this article, Christopher Pleiman, Daniele D'Ambrosio and John Cambier consolidate new findings regarding BCR structure and signal transduction.
引用
收藏
页码:393 / 399
页数:7
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