NEUROIMAGING STUDY OF MYOTONIC-DYSTROPHY .2. MRI MEASUREMENTS OF THE BRAIN

被引：11

作者：

HASHIMOTO, T

TAYAMA, M

MIYAZAKI, M

MURAKAWA, K

KAWAI, H

NISHITANI, H

KURODA, Y

机构：

[1] UNIV TOKUSHIMA,SCH MED,DEPT INTERNAL MED,TOKUSHIMA,JAPAN

[2] UNIV TOKUSHIMA,SCH MED,DEPT RADIOL,TOKUSHIMA 770,JAPAN

来源：

BRAIN & DEVELOPMENT | 1995年 / 17卷 / 01期

关键词：

MYOTONIC DYSTROPHY; MAGNETIC RESONANCE IMAGING; BRAIN MEASUREMENT; PENS; CORPUS CALLOSUM;

D O I：

10.1016/0387-7604(94)00097-H

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The brain of patients with adult type myotonic dystrophy was measured using MRT, and compared with age- and sex-matched controls, The width of the cerebrum, and the areas of the corpus callosum, pens and pituitary gland were significantly smaller in adult-type myotonic dystrophy than in the controls, The IQ of the patients with adult-type myotonic dystrophy was lower than that of controls, These results demonstrate a decreased volume of the brain and pituitary glands in myotonic dystrophy, These findings suggest a causal relationship for the mental retardation and endocrine dysfunction that may occur.

引用

收藏

页码：28 / 32

页数：5

相关论文

共 16 条

[1] SHORT-LATENCY SOMATOSENSORY EVOKED-POTENTIALS IN DYSTROPHIA MYOTONICA [J].

BARTEL, PR ;

LOTZ, BP ;

VANDERMEYDEN, CH .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1984, 47 (05) :524-529

[2]

Caughey JE, 1963, DYSTROPHIA MYOTONICA

[3] HYPOTHALAMIC-PITUITARY-GONADAL FUNCTION IN PATIENTS WITH MYOTONIC-DYSTROPHY [J].

FEBRES, F ;

SCAGLIA, H ;

LISKER, R ;

ESPINOSA, J ;

MORATO, T ;

SHKUROVICH, M ;

PEREZPALACIOS, G .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1975, 41 (05) :833-840

[4] AN UNSTABLE TRIPLET REPEAT IN A GENE RELATED TO MYOTONIC MUSCULAR-DYSTROPHY [J].

FU, YH ;

PIZZUTI, A ;

FENWICK, RG ;

KING, J ;

RAJNARAYAN, S ;

DUNNE, PW ;

DUBEL, J ;

NASSER, GA ;

ASHIZAWA, T ;

DEJONG, P ;

WIERINGA, B ;

KORNELUK, R ;

PERRYMAN, MB ;

EPSTEIN, HF ;

CASKEY, CT .

SCIENCE, 1992, 255 (5049) :1256-1258

[5] MORPHOLOGICAL EVIDENCE FOR BRAIN-STEM INVOLVEMENT IN INFANTILE-AUTISM [J].

GAFFNEY, GR ;

KUPERMAN, S ;

TSAI, LY ;

MINCHIN, S .

BIOLOGICAL PSYCHIATRY, 1988, 24 (05) :578-586

[6] CENTRAL NERVOUS-SYSTEM MAGNETIC-RESONANCE IMAGING FINDINGS IN MYOTONIC-DYSTROPHY [J].

GLANTZ, RH ;

WRIGHT, RB ;

HUCKMAN, MS ;

GARRON, DC ;

SIEGEL, IM .

ARCHIVES OF NEUROLOGY, 1988, 45 (01) :36-37

[7] MAGNETIC-RESONANCE IMAGING AND CLINICAL CORRELATES OF INTELLECTUAL IMPAIRMENT IN MYOTONIC-DYSTROPHY [J].

HUBER, SJ ;

KISSEL, JT ;

SHUTTLEWORTH, EC ;

CHAKERES, DW ;

CLAPP, LE ;

BROGAN, MA .

ARCHIVES OF NEUROLOGY, 1989, 46 (05) :536-540

[8] A MORPHOMETRIC CT STUDY OF DOWNS-SYNDROME SHOWING SMALL POSTERIOR-FOSSA AND CALCIFICATION OF BASAL GANGLIA [J].

IESHIMA, A ;

KISA, T ;

YOSHINO, K ;

TAKASHIMA, S ;

TAKESHITA, K .

NEURORADIOLOGY, 1984, 26 (06) :493-498

[9]

NASS RD, 1984, HDB PHYSL NERVOUS SY, V5, P701

[10] HIGH-RESOLUTION MAGNETIC-RESONANCE IMAGING FINDINGS IN JUVENILE-ONSET MYOTONIC-DYSTROPHY [J].

PETERSON, AC ;

DEW, MS ;

POWE, LK .

ARCHIVES OF NEUROLOGY, 1989, 46 (05) :481-482