THE ROLE OF IRON IN INFECTION

被引：77

作者：

WEINBERG, ED

WEINBERG, GA

机构：

[1] Dept Biology Program Med Sciences, Indiana University, Bloomington

来源：

CURRENT OPINION IN INFECTIOUS DISEASES | 1995年 / 8卷 / 03期

关键词：

D O I：

10.1097/00001432-199506000-00004

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The availability of iron plays a critical role in host-parasite relations. Microbial pathogens cannot replicate without acquiring iron from their vertebrate hosts, and several strategies of microbial iron acquisition have evolved. Vertebrate animals have developed elaborate strategies to withhold iron from invading pathogens while retaining their own access to the metal. This review focuses on recent data from studies of both microbial iron-acquisition mechanisms and the vertebrate host's iron-withholding defense system components.

引用

页码：164 / 169

页数：6