ACTIVATION BY THYMIDINE KINASE AND POTENT ANTIHERPETIC ACTIVITY OF 2'-NOR-2'-DEOXYGUANOSINE (2'NDG)

被引：203

作者：

ASHTON, WT

KARKAS, JD

FIELD, AK

TOLMAN, RL

机构：

[1] MERCK INST THERAPEUT RES, RAHWAY, NJ 07065 USA

[2] MERCK INST THERAPEUT RES, W POINT, PA 19486 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1982年 / 108卷 / 04期

关键词：

D O I：

10.1016/S0006-291X(82)80109-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

收藏

页码：1716 / 1721

页数：6

相关论文

共 14 条

[1] DIFFERENTIAL ACTIVITY OF POTENTIAL ANTI-VIRAL NUCLEOSIDE ANALOGS ON HERPES-SIMPLEX VIRUS-INDUCED AND HUMAN CELLULAR THYMIDINE KINASES
CHENG, YC
DUTSCHMAN, G
FOX, JJ
WATANABE, KA
MACHIDA, H
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1981, 20 (03) : 420 - 423
[2] CHENG YC, 1976, J BIOL CHEM, V251, P2605
[3] FALKE D, 1980, DEV ANTIVIRAL THERAP, P3
[4] AN IMPROVED FUSION METHOD FOR THE SYNTHESIS OF PURINE NUCLEOSIDES - THE ACID-CATALYZED REACTIONS OF N(7)-ACYLPURINES OR N(9)-ACYLPURINES WITH ACYLATED SUGARS
ISHIDO, Y
HOSONO, A
ISOME, S
MARUYAMA, A
SATO, T
[J]. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1964, 37 (09) : 1389 - 1390
[5] PURINE ACYCLIC NUCLEOSIDES - NITROGEN ISOSTERES OF 9-[(2-HYDROXYETHOXY)METHYL]GUANINE AS CANDIDATE ANTIVIRALS
KELLEY, JL
KROCHMAL, MP
SCHAEFFER, HJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (12) : 1528 - 1531
[6] KHAIKINA MB, 1966, IZV VYSSHIKH UCHEBN, V9, P418
[7] KRASNY HC, 1981, J PHARMACOL EXP THER, V216, P281
[8] PHARMACOKINETICS AND TOLERANCE OF ACYCLOVIR, A NEW ANTI-HERPESVIRUS AGENT, IN HUMANS
LASKIN, OL
LONGSTRETH, JA
SARAL, R
DEMIRANDA, P
KEENEY, R
LIETMAN, PS
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1982, 21 (03) : 393 - 398
[9] NISHIMURA T, 1962, CHEM PHARM BULL, V12, P352
[10] 9-(2-HYDROXYETHOXYMETHYL)GUANINE ACTIVITY AGAINST VIRUSES OF HERPES GROUP
SCHAEFFER, HJ
BEAUCHAMP, L
MIRANDA, PD
ELION, GB
BAUER, DJ
COLLINS, P
[J]. NATURE, 1978, 272 (5654) : 583 - 585