NAPHTHALENE-CATALYZED LITHIATION OF PHENONE IMINES IN THE PRESENCE OF CARBONYL-COMPOUNDS - PREPARATION OF 1,2-AMINOALCOHOLS

被引：48

作者：

GUIJARRO, D ^{[1
]}

YUS, M ^{[1
]}

机构：

[1] UNIV ALICANTE,FAC CIENCIAS,DEPT QUIM ORGAN,APDO 99,E-03080 ALICANTE,SPAIN

来源：

TETRAHEDRON | 1993年 / 49卷 / 35期

关键词：

D O I：

10.1016/S0040-4020(01)87249-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The lithiation of different phenone imines 1 with an excess of lithium powder and a catalytic amount (8 mol %) of naphthalene in the presence of several carbonyl compounds 2 in tetrahydrofuran at temperatures ranging between -78 and 20-degrees-C leads, after hydrolysis with water, to the corresponding 1,2-aminoalcohols 3 in moderate yields.

引用

页码：7761 / 7768

页数：8

共 25 条

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