ESCHERICHIA-COLI TRANSCRIPTION FACTOR THAT BOTH ACTIVATES FATTY-ACID SYNTHESIS AND REPRESSES FATTY-ACID DEGRADATION

被引：93

作者：

HENRY, MF ^{[1
]}

CRONAN, JE ^{[1
]}

机构：

[1] UNIV ILLINOIS,DEPT BIOCHEM,URBANA,IL 61801

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1991年 / 222卷 / 04期

基金：

美国国家卫生研究院;

关键词：

ESCHERICHIA-COLI; TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; FADR; FATTY ACID SYNTHESIS;

D O I：

10.1016/0022-2836(91)90574-P

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The fadR gene of Escherichia coli encodes a protein that acts as a negative regulator (repressor) of the inducible β-oxidation pathway. We report that the FadR protein also functions as a positive transcriptional activator of the fabA gene, which encodes the enzyme introducing the double bond of the unsaturated fatty acids of E. coli. © 1991.

引用

页码：843 / 849

页数：7

共 20 条

[1] MUTATION TO EXTENDED HOST RANGE AND THE OCCURRENCE OF PHENOTYPIC MIXING IN THE TEMPERATE COLIPHAGE LAMBDA [J].