A HIGHLY SELECTIVE PROTOCOL FOR THE DEPROTECTION OF BOC-PROTECTED AMIDES AND CARBAMATES

被引：81

作者：

STAFFORD, JA

BRACKEEN, MF

KARANEWSKY, DS

VALVANO, NL

机构：

[1] Glaxo Research Institute, Research Triangle Park, NC 27709

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 49期

关键词：

D O I：

10.1016/S0040-4039(00)61498-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A BOC-protected amide or carbamate undergoes mild and selective deprotection by treatment with catalytic Mg(ClO4)(2) in acetonitrile. Simple BOC-protected amines are not affected by these conditions.

引用

页码：7873 / 7876

页数：4

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