POLYMERIC MEMBRANE SODIUM-SELECTIVE ELECTRODES BASED ON LIPOPHILIC CALIX[4]ARENE DERIVATIVES

Three kinds of lipophilic calix[4]aryl ester and amide derivatives (1–3) have been designed for Na+-selective polymeric membrane electrodes. The calixarene ionophores have thus proved to be excellent Na+ neutral carriers. Furthermore, selection of the electrode membrane conditions such as membrane solvents and lipophilic salts allowed high Na+ selectivities against K+, the selectivity coefficient for Na+ with respect to K+ being 3.8 × 10-3 in the electrode based on calix[4]aryl decyl ester 1. The calixarene-based Na+-selective electrode was successfully applied to Na+ assay in human blood sera. © 1990, American Chemical Society. All rights reserved.