DELETION MUTANTS OF HARVEY RAS P21 PROTEIN REVEAL THE ABSOLUTE REQUIREMENT OF AT LEAST 2 DISTANT REGIONS FOR GTP-BINDING AND TRANSFORMING ACTIVITIES

被引：44

作者：

LACAL, JC

ANDERSON, PS

AARONSON, SA

机构：

来源：

EMBO JOURNAL | 1986年 / 5卷 / 04期

关键词：

D O I：

10.1002/j.1460-2075.1986.tb04267.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：679 / 687

页数：9

共 47 条

[1] TUMORIGENIC TRANSFORMATION OF MAMMALIAN-CELLS INDUCED BY A NORMAL HUMAN-GENE HOMOLOGOUS TO THE ONCOGENE OF HARVEY MURINE SARCOMA-VIRUS [J].

CHANG, EH ;

FURTH, ME ;

SCOLNICK, EM ;

LOWY, DR .

NATURE, 1982, 297 (5866) :479-483

[2] ANTIBODIES SPECIFIC FOR AMINO-ACID 12 OF THE RAS ONCOGENE PRODUCT INHIBIT GTP BINDING [J].

CLARK, R ;

WONG, G ;

ARNHEIM, N ;

NITECKI, D ;

MCCORMICK, F .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (16) :5280-5284

[3] RAS-RELATED GENE-SEQUENCES IDENTIFIED AND ISOLATED FROM SACCHAROMYCES-CEREVISIAE [J].

DEFEOJONES, D ;

SCOLNICK, EM ;

KOLLER, R ;

DHAR, R .

NATURE, 1983, 306 (5944) :707-709

[4] MICROINJECTION OF THE ONCOGENE FORM OF THE HUMAN H-RAS (T-24) PROTEIN RESULTS IN RAPID PROLIFERATION OF QUIESCENT CELLS [J].

FERAMISCO, JR ;

GROSS, M ;

KAMATA, T ;

ROSENBERG, M ;

SWEET, RW .

CELL, 1984, 38 (01) :109-117

[5] TRANSIENT REVERSION OF RAS ONCOGENE-INDUCED CELL-TRANSFORMATION BY ANTIBODIES SPECIFIC FOR AMINO-ACID 12 OF RAS PROTEIN [J].

FERAMISCO, JR ;

CLARK, R ;

WONG, G ;

ARNHEIM, N ;

MILLEY, R ;

MCCORMICK, F .

NATURE, 1985, 314 (6012) :639-642

[6] ACTIVATION OF RAS GENES IN HUMAN-TUMORS DOES NOT AFFECT LOCALIZATION, MODIFICATION, OR NUCLEOTIDE BINDING-PROPERTIES OF P21 [J].

FINKEL, T ;

DER, CJ ;

COOPER, GM .

CELL, 1984, 37 (01) :151-158

[7] MOLECULAR-CLONING AND SEQUENCE-ANALYSIS OF A RAS GENE FROM SCHIZOSACCHAROMYCES-POMBE [J].

FUKUI, Y ;

KAZIRO, Y .

EMBO JOURNAL, 1985, 4 (03) :687-691

[8] MONOCLONAL-ANTIBODIES TO THE P21 PRODUCTS OF THE TRANSFORMING GENE OF HARVEY MURINE SARCOMA-VIRUS AND OF THE CELLULAR RAS GENE FAMILY [J].

FURTH, ME ;

DAVIS, LJ ;

FLEURDELYS, B ;

SCOLNICK, EM .

JOURNAL OF VIROLOGY, 1982, 43 (01) :294-304

[9] A YEAST GENE ENCODING A PROTEIN HOMOLOGOUS TO THE HUMAN C-HAS/BAS PROTO-ONCOGENE PRODUCT [J].

GALLWITZ, D ;

DONATH, C ;

SANDER, C .

NATURE, 1983, 306 (5944) :704-707

[10] EXPRESSION OF THE NORMAL HUMAN SIS/PDGF-2 CODING SEQUENCE INDUCES CELLULAR-TRANSFORMATION [J].

GAZIT, A ;

IGARASHI, H ;

CHIU, IM ;

SRINIVASAN, A ;

YANIV, A ;

TRONICK, SR ;

ROBBINS, KC ;

AARONSON, SA .

CELL, 1984, 39 (01) :89-97

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