IMMUNOHISTOCHEMICAL LOCALIZATION OF PACAP IN THE OVINE DIGESTIVE-SYSTEM

被引：73

作者：

KOVES, K

ARIMURA, A

VIGH, S

SOMOGYVARIVIGH, A

MILLER, J

机构：

[1] TULANE UNIV,HERBERT CTR,US JAPAN BIOMED RES LABS,BLDG 30,3705 MAIN ST,BELLE CHASSE,LA 70037

[2] TULANE UNIV,SCH MED,DEPT MED,NEW ORLEANS,LA 70112

[3] TULANE UNIV,SCH MED,DEPT ANAT,NEW ORLEANS,LA 70112

[4] TULANE UNIV,SCH MED,DEPT PHYSIOL,NEW ORLEANS,LA 70112

[5] LOUISIANA STATE UNIV,SCH VET MED,DEPT EPIDEMIOL,BATON ROUGE,LA 70803

来源：

PEPTIDES | 1993年 / 14卷 / 03期

关键词：

PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; SHEEP; DIGESTIVE SYSTEM; IMMUNOHISTOCHEMISTRY;

D O I：

10.1016/0196-9781(93)90131-Y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The localization of immunoreactive PACAP (PACAP-IR) in the entire length of the sheep gastrointestinal tract and the pancreas was studied by an immunohistochemical method. PACAP-IR-containing nerve fibers innervated the longitudinal smooth muscle layer of the mucosa in the esophagus, stomach, and small and large intestines, the muscular layer of the stomach and intestine, Brunner's gland of the duodenum, and the walls of small arteries. PACAP-IR fibers also innervated the exocrine acini, islets of Langerhans, and the small arteries in the connective tissue septa of the pancreas. These findings suggest a regulatory role of PACAP in the digestive system.

引用

页码：449 / 455

页数：7

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