HOST-PARASITE RELATIONSHIPS IN AMEBIASIS - CONFERENCE REPORT

被引：13

作者：

PETRI, WA

CLARK, CG

DIAMOND, LS

机构：

[1] UNIV VIRGINIA,HLTH SCI CTR,DEPT MICROBIOL,CHARLOTTESVILLE,VA 22908

[2] NIAID,PARASIT DIS LAB,BETHESDA,MD 20892

来源：

JOURNAL OF INFECTIOUS DISEASES | 1994年 / 169卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1093/infdis/169.3.483

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Entamoeba histolytica has been redescribed as the separate species E. histolytica and Entamoeba dispar. E. dispar is apparently never invasive in humans, while E. histolytica is the etiologic agent of amebic colitis and liver abscess. Virulence factors that may enable E. histolytica to invade include a galactose-specific adhesin, secreted proteases, extracellular matrix receptors, and a cell surface lipophosphoglycan. Progress in vaccine development includes the identification of the cysteine-rich domain of the adhesin and the serine-rich surface protein as protective antigens.

引用

页码：483 / 484

页数：2