PARABOLIC GROWTH OF A SELF-REPLICATING HEXADEOXYNUCLEOTIDE BEARING A 3',5'-PHOSPHOAMIDATE LINKAGE

被引：155

作者：

VONKIEDROWSKI, G

WLOTZKA, B

HELBING, J

MATZEN, M

JORDAN, S

机构：

[1] Institute for Organic Chemistry of the University, Goettingen, W-3400

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1991年 / 30卷 / 04期

关键词：

D O I：

10.1002/anie.199104231

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel type of autocatalytic growth, which is distinguishable from exponential growth and has implications for theories on the origin of life, is revealed by self-replication experiments based on nonenzymatic template-directed reactions of oligonucleotide derivatives. The sketch on the right shows the general mechanism of a minimal system for self-replication.

引用

页码：423 / 426

页数：4

共 14 条

[1] EIGEN M, 1979, HYPERCYCLE PRINCIPLE, P12
[2] HELBING J, 1990, THESIS U GOETTINGEN
[3] NONENZYMATIC TEMPLATE-DIRECTED SYNTHESIS OF INFORMATIONAL MACROMOLECULES
JOYCE, GF
[J]. COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1987, 52 : 41 - 51
[4] RNA EVOLUTION AND THE ORIGINS OF LIFE
JOYCE, GF
[J]. NATURE, 1989, 338 (6212) : 217 - 224
[5] MATZEN M, UNPUB
[6] ORGEL LE, 1987, COLD SPRING HARB SYM, V7, P9
[7] SUB-EXPONENTIAL GROWTH AND COEXISTENCE OF NON-ENZYMATICALLY REPLICATING TEMPLATES
SZATHMARY, E
GLADKIH, I
[J]. JOURNAL OF THEORETICAL BIOLOGY, 1989, 138 (01) : 55 - 58
[8] A SELF-REPLICATING SYSTEM
TJIVIKUA, T
BALLESTER, P
REBEK, J
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (03) : 1249 - 1250
[9] von Kiedrowski G., 1990, 40 JAHRE FONDS CHEM, P197
[10] von Kiedrowski G. A, 1986, ANGEW CHEM, V98, P932

← 1 2 →