THE PROGNOSTIC USE OF A LACTATE INFUSION IN PATIENTS WITH SEVERE HEPATORENAL FAILURE

被引：4

作者：

DAVENPORT, A

DAVISON, AM

WILL, EJ

机构：

[1] Department of Renal Medicine, St. James's University Hospital, Leeds, England

来源：

RENAL FAILURE | 1991年 / 13卷 / 2-3期

关键词：

D O I：

10.3109/08860229109022155

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We have used machine hemofiltration (MHF) with lactate-buffered hemofiltration replacement solution in the management of four patients with severe hepatorenal failure. Hyperlactatemia developed in all four patients. However, consecutive treatments were associated with increasing blood lactate values postfiltration in the two patients who died and with a fall in the lactates in the two patients who survived. The survivors had lower postfiltration blood lactates 3.2 +/- 0.2 mmol/L (mean +/- SEM) compared to the nonsurvivors, 5.3 +/- 0.5 mmol/L (p < 0.01). This suggests that the measurement of blood lactate following a lactate challenge may be of prognostic significance in patients with severe hepatorenal failure.

引用

页码：111 / 118

页数：8

共 31 条

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