AZASTEROIDS - STRUCTURE-ACTIVITY-RELATIONSHIPS FOR INHIBITION OF 5-ALPHA-REDUCTASE AND OF ANDROGEN RECEPTOR-BINDING

被引：282

作者：

RASMUSSON, GH ^{[1
]}

REYNOLDS, GF ^{[1
]}

STEINBERG, NG ^{[1
]}

WALTON, E ^{[1
]}

PATEL, GF ^{[1
]}

LIANG, TM ^{[1
]}

CASCIERI, MA ^{[1
]}

CHEUNG, AH ^{[1
]}

BROOKS, JR ^{[1
]}

BERMAN, C ^{[1
]}

机构：

[1] MERCK SHARP & DOHME RES LABS,DEPT BIOCHEM ENDOCRINOL,RAHWAY,NJ 07065

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 11期

关键词：

D O I：

10.1021/jm00161a028

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：2298 / 2315

页数：18

相关论文

共 40 条

[1] CONVENIENT METHOD FOR PREPARATION OF KETONES BY REACTION OF GRIGNARD-REAGENTS WITH CARBOXYLIC-ACID DERIVATIVES
ARAKI, M
SAKATA, S
TAKEI, H
MUKAIYAM.T
[J]. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1974, 47 (07) : 1777 - 1780
[2] ALDOSTERONE ANTAGONISTS. 2'3' ALPHA-TETRAHYDROFURAN-2'-SPIRO-17-(4-ANDROSTEN-3-ONE) AND RELATED COMPOUNDS
ARTH, GE
SCHWAM, H
GLITZER, M
SARETT, LH
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1963, 6 (05) : 617 - &
[3] ARTH GE, 1974, TETRAHEDRON LETT, P291
[4] OXIDATION OF AZASTEROID LACTAMS AND ALCOHOLS WITH BENZENESELENINIC ANHYDRIDE
BACK, TG
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1981, 46 (07) : 1442 - 1446
[5] TESTOSTERONE - A MAJOR DETERMINANT OF EXTRA-GENITAL SEXUAL DIMORPHISM
BARDIN, CW
CATTERALL, JF
[J]. SCIENCE, 1981, 211 (4488) : 1285 - 1294
[6] BERKOVITZ GD, 1984, J ANDROL, V5, P171
[7] BERTICS BJ, 1984, J BIOL CHEM, V259, P107
[8] A HIGH-AFFINITY INHIBITOR OF PITUITARY PROGESTERONE 5-ALPHA-REDUCTASE
BERTICS, PJ
EDMAN, CF
KARAVOLAS, HJ
[J]. ENDOCRINOLOGY, 1984, 114 (01) : 63 - 69
[9] Bolt CC, 1938, RECL TRAV CHIM PAY-B, V57, P905
[10] RESEARCHES ON ACETYLENIC COMPOUNDS .1. THE PREPARATION OF ACETYLENIC KETONES BY OXIDATION OF ACETYLENIC CARBINOLS AND GLYCOLS
BOWDEN, K
HEILBRON, IM
JONES, ERH
WEEDON, BCL
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1946, (JAN): : 39 - 45

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