EFFECTS OF URSODEOXYCHOLIC ACID ON LIVER-FUNCTION IN PATIENTS WITH CYSTIC-FIBROSIS AND CHRONIC CHOLESTASIS

被引：64

作者：

GALABERT, C

MONTET, JC

LENGRAND, D

LECUIRE, A

SOTTA, C

FIGARELLA, C

CHAZALETTE, JP

机构：

[1] HOP LYON, HOP RENEE SABRAN, BIOCHIM LAB, HYERES, FRANCE

[2] HOP LYON, HOP RENEE SABRAN, CTR ETUD RECH MUCOVISCIDOSE, HYERES, FRANCE

[3] INSERM, RECH GLANDES EXOCRINES GRP, F-13258 MARSEILLE 09, FRANCE

[4] HOP LYON, HOP CROIX ROUSSE, Lyon, FRANCE

来源：

JOURNAL OF PEDIATRICS | 1992年 / 121卷 / 01期

关键词：

D O I：

10.1016/S0022-3476(05)82561-2

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Ursodeoxycholic acid, 10 to 20 mg/kg per day, was administered for 1 year to 22 patients with cystic fibrosis and chronic cholestasis, resulting in significantly improved liver enzyme values. However, evidence of cholestasis continued, as shown by the pattern of alkaline phosphatase isoenzymes.

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页码：138 / 141

页数：4

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