ANTIMICROBIAL COMPOUNDS FROM PETALOSTEMUM-PURPUREUM

被引：28

作者：

HUFFORD, CD ^{[1
]}

JIA, YM ^{[1
]}

CROOM, EM ^{[1
]}

MUHAMMED, I ^{[1
]}

OKUNADE, AL ^{[1
]}

CLARK, AM ^{[1
]}

ROGERS, RD ^{[1
]}

机构：

[1] NO ILLINOIS UNIV,DEPT CHEM,DE KALB,IL 60115

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 11期

关键词：

D O I：

10.1021/np50101a003

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

EtOH extracts of Petalostemum purpureum demonstrated antimicrobial activity against bacteria and fungi. Bioassay-directed fractionation led to the isolation of petalostemumol [1] as the active constituent. Its structure was determined by a single crystal X-ray diffraction analysis. A minor component designated petalostemumol G [3] is believed to be an artifact of the isolation procedure. Its structure was confirmed by a single crystal X-ray analysis of its pentamethylether 2. A number of derivatives of 1 and 3, including the Me- and benzylethers and acetates, were prepared.

引用

页码：1878 / 1889

页数：12

共 13 条

[1]

BHARDWAJ DK, 1982, INDIAN J CHEM B, V21, P493

[2] ANTI-MICROBIAL ACTIVITY OF PHENOLIC CONSTITUENTS OF MAGNOLIA-GRANDIFLORA L [J].