NOVEL REACTIVE SILYL ENOLATES - HIGHLY STEREOSELECTIVE ALDOL AND MICHAEL REACTIONS WITHOUT CATALYSTS

被引：21

作者：

KOBAYASHI, S

NISHIO, K

机构：

[1] Department of Applied Chemistry, Faculty of Science, Science University of Tokyo (SUT), Tokyo 162, Kagurazaka, Shinjuku-ku

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 10期

关键词：

D O I：

10.1021/jo00062a002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Novel silyl enolates, prepared in situ from ketones and dimethylsilyl ditriflate (Me2Si(OTf)2) in the presence of a tertiary amine, reacted smoothly with electrophiles such as aldehydes, acetals, or alpha,beta-unsaturated ketones without catalyst at -78-degrees-C to afford the corresponding adducts in high yields and with high selectivities.

引用

页码：2647 / 2649

页数：3

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