RAS SIGNALING AND NF1

被引：88

作者：

MCCORMICK, F

机构：

[1] Onyx Pharmaceuticals, Richmond, CA 94806

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1995年 / 5卷 / 01期

关键词：

D O I：

10.1016/S0959-437X(95)90053-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The gene responsible for the hereditary disease neurofibromatosis type 1 (NF1) has been well characterized as a regulator of Ras protein activity. Many aspects of the disease seem to be caused by misregulation of Ras as a result or NF1 mutation. Other aspects, however, point at functions for the NF1 protein that have yet to be discovered.

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页码：51 / 55

页数：5

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