3 NEW OLEANENE GLYCOSIDES FROM SOPHORA-FLAVESCENS

被引：28

作者：

DING, Y

TIAN, RH

KINJO, JN

NOHARA, T ^{[1
]}

KITAGAWA, I

机构：

[1] KUMAMOTO UNIV, FAC PHARMACEUT SCI, OE HONMACHI 5-1, KUMAMOTO 862, JAPAN

[2] OSAKA UNIV, FAC PHARMACEUT SCI, SUITA, OSAKA 565, JAPAN

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1992年 / 40卷 / 11期

关键词：

SOPHORA-FLAVESCENS; LEGUMINOSAE; SOPHORAFLAVOSIDE; OXYTROGENIN; 3-BETA; 22-BETA; 24-TRIHYDROXYOLEAN-12-EN-29-OIC ACID; BISDEMOSIDE; OLEANENE GLYCOSIDE;

D O I：

10.1248/cpb.40.2990

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three new oleanene glycosides, sophoraflavosides II-IV (2-4) were isolated together with sophoraflavoside I (1) as the corresponding methyl ester forms from Sophorae Radix, the fresh roots of Sophora flavescens AITON (Leguminosae). Their structures have been elucidated as oxytrogenin 3-0-alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-galactopyranosyl-(1 --> 2)-beta-D-glucuronopyranoside (2), 3-0-alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-galactopyranosyl-(1 --> 2)-beta-D-glucuronopyranosyl oxytrogenin 22-0-alpha-L-arabinopyranoside (3) and 3-0-alpha-L-rhamnopyranosYl-(1 --> 2)-beta-D-galactopyranosyl-(1 --> 2)-beta-D-glucuronopyranosyl oxytrogenin 22-0-beta-D-glucopyranosyl-(1 --> 2)-alpha-L-arabinopyranoside (4), along with unambiguous characterization as 3beta,22beta,24-trihydroxyolean-12-en-29-oic acid for their sapogenol, named oxytrogenin (5) on the bases of chemical reactions and spectral analyses.

引用

页码：2990 / 2994

页数：5

共 9 条

[1]

BUDZIKIEWICZ H, 1964, STRUCTURE ELUCIDATIO, V2, P121

[2] TRITERPENE GLYCOSIDES FROM THE BARK OF ROBINIA-PSEUDO-ACACIA L .1. [J].

CUI, BL ;

KINJO, J ;

NOHARA, T .

CHEMICAL & PHARMACEUTICAL BULLETIN, 1992, 40 (11) :2995-2999

[3]

HARA S, 1987, CHEM PHARM BULL, V35, P501

[4]

KASAI R, 1977, TETRAHEDRON LETT, P175

[5]

SUN RQ, 1990, PHYTOCHEMISTRY, V29, P2032, DOI 10.1016/0031-9422(90)85065-N

[6]

TAKESHITA T, 1989, CHEM PHARM BULL, V37, P846

[7]

TORI K, 1977, TETRAHEDRON LETT, P179

[8]

YOSHIKAWA M, 1985, CHEM PHARM BULL, V33, P4267

[9]

1977, DICT CHINESE CRUDE D, P1283

← 1 →