IMMUNOLOGICAL MODULATION AND EVASION BY HELMINTH-PARASITES IN HUMAN-POPULATIONS

被引:461
作者
MAIZELS, RM [1 ]
BUNDY, DAP [1 ]
SELKIRK, ME [1 ]
SMITH, DF [1 ]
ANDERSON, RM [1 ]
机构
[1] UNIV LONDON IMPERIAL COLL SCI TECHNOL & MED,WELLCOME RES CTR PARASIT INFECT,DEPT BIOCHEM,LONDON SW7 2BB,ENGLAND
基金
英国惠康基金;
关键词
D O I
10.1038/365797a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Helminth parasites are highly prevalent in human communities in developing countries. In an endemic area an infected individual may harbour parasitic worms for most of his or her life, and the ability of these infections to survive immunological attack has long been a puzzle. But new techniques are starting to expose the diverse mechanisms by which these agents modulate or evade their hosts' defences, creating a dynamic interaction between the human immune system and the parasite population.
引用
收藏
页码:797 / 805
页数:9
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