THE STEREOSELECTIVE SYNTHESIS OF FUNCTIONALIZED VICINAL DIAMINE SYSTEMS BY THE DOUBLE ALLYLATION REACTIONS OF PROTECTED 1,2-BISIMINE PRECURSORS

被引：68

作者：

NEUMANN, WL

ROGIC, MM

DUNN, TJ

机构：

[1] Mallinckrodt Medical Inc., St. Louis

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 42期

关键词：

D O I：

10.1016/S0040-4039(00)79412-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A diastereoselective synthesis of vicinal diamines via the reactions of allylic Grignard reagents with readily available "protected" 1,2-bisimines has been developed. This method has been extended to preparing optically pure diamines by the use of chiral 1,2-bisimine precursors.

引用

页码：5865 / 5868

页数：4

共 13 条

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