ENDOGENOUS ALKALOIDS IN MAN .7. 1-TRICHLOROMETHYL-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE - A POTENTIAL CHLORAL-DERIVED INDOLE ALKALOID IN MAN

被引：41

作者：

BRINGMANN, G

HILLE, A

机构：

[1] Institut für Organische Chemie, Universität Würzburg, Würzburg

来源：

ARCHIV DER PHARMAZIE | 1990年 / 323卷 / 09期

关键词：

D O I：

10.1002/ardp.19903230903

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

The trichloromethyl tetrahydro‐β‐carboline 5, an imaginable, chloral‐derived mammalian indol “alkaloid”, was prepared in high yields and was shown to be formed even under mild, physiological conditions, in aqueous medium. For its detection in low concentrations, a chromatographic procedure was elaborated. Furthermore, its potential metabolite 8 was synthesized for the first time. Copyright © 1990 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim

引用

页码：567 / 569

页数：3

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[2]

AIRAKSINEN MM, 1981, MED BIOL, V59, P21

[3]

HPLC-ANALYSIS OF HIGHLY POLAR PYRIDOXYL ALKALOIDS IN MAMMALIAN BLOOD [J].