STRUCTURE OF A SINGLE AMINO-ACID MUTANT OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.5-A RESOLUTION - IMPLICATIONS FOR THE COOPERATIVE MECHANISM

被引：13

作者：

GOUAUX, JE

LIPSCOMB, WN

MIDDLETON, SA

KANTROWITZ, ER

机构：

[1] HARVARD UNIV,GIBBS CHEM LAB,CAMBRIDGE,MA 02138

[2] BOSTON COLL,DEPT CHEM,CHESTNUT HILL,MA 02167

来源：

BIOCHEMISTRY | 1989年 / 28卷 / 04期

关键词：

D O I：

10.1021/bi00430a056

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1798 / 1803

页数：6

共 29 条

[1] L-ALANOSINE - A NONCOOPERATIVE SUBSTRATE FOR ESCHERICHIA-COLI ASPARTATE-TRANSCARBAMYLASE [J].

BAILLON, J ;

TAUC, P ;

HERVE, G .

BIOCHEMISTRY, 1985, 24 (25) :7182-7187

[2] CARBAMYL PHOSPHATE - AN ALLOSTERIC SUBSTRATE FOR ASPARTATE TRANSCARBAMYLASE OF ESCHERICHIA COLI [J].

BETHELL, MR ;

SMITH, KE ;

WHITE, JS ;

JONES, ME .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1968, 60 (04) :1442-&

[3]

BLACKBURN MN, 1977, BIOCHEMISTRY-US, V16, P5084, DOI 10.1021/bi00642a022

[4] CRYSTALLOGRAPHIC R-FACTOR REFINEMENT BY MOLECULAR-DYNAMICS [J].

BRUNGER, AT ;

KURIYAN, J ;

KARPLUS, M .

SCIENCE, 1987, 235 (4787) :458-460

[5] HOMOTROPIC EFFECTS IN ASPARTATE TRANSCARBAMOYLASE - WHAT HAPPENS WHEN THE ENZYME BINDS A SINGLE MOLECULE OF THE BISUBSTRATE ANALOG N-PHOSPHONACETYL-L-ASPARTATE [J].

FOOTE, J ;

SCHACHMAN, HK .

JOURNAL OF MOLECULAR BIOLOGY, 1985, 186 (01) :175-184

[6]

FOOTE J, 1985, J BIOL CHEM, V260, P9624

[7] AN ALTERNATIVE METHOD OF SOLVING LAYER SCALING EQUATIONS OF HAMILTON ROLLETT AND SPARKS [J].

FOX, GC ;

HOLMES, KC .

ACTA CRYSTALLOGRAPHICA, 1966, 20 :886-&

[8] ALLOSTERIC INTERACTIONS IN ASPARTATE TRANSCARBAMYLASE .2. EVIDENCE FOR DIFFERENT CONFORMATIONAL STATES OF PROTEIN IN PRESENCE AND ABSENCE OF SPECIFIC LIGANDS [J].

GERHART, JC ;

SCHACHMAN, HK .

BIOCHEMISTRY, 1968, 7 (02) :538-+

[9] DISTINCT SUBUNITS FOR REGULATION AND CATALYTIC ACTIVITY OF ASPARTATE TRANSCARBAMYLASE [J].

GERHART, JC ;

SCHACHMAN, HK .

BIOCHEMISTRY, 1965, 4 (06) :1054-+

[10]

GERHART JC, 1962, J BIOL CHEM, V237, P891

← 1 2 3 →