TREMOR - AN ALTERNATIVE APPROACH FOR INVESTIGATING ADRENERGIC-MECHANISMS IN THYROTOXICOSIS

被引：8

作者：

ABILA, B

LAZARUS, JH

KINGSWOOD, JC

MARSHALL, RW

WILSON, JF

RICHENS, A

机构：

[1] UNIV WALES, COLL MED, DEPT PHARMACOL & THERAPEUT, CARDIFF CF4 4XN, WALES

[2] UNIV WALES, COLL MED, DEPT MED, CARDIFF CF4 4XN, WALES

来源：

CLINICAL SCIENCE | 1985年 / 69卷 / 04期

关键词：

D O I：

10.1042/cs0690459

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

1. The effects of nadolol (or placebo) and carbimazole on thyrotoxic tremor were investigated in 18 thyrotoxic patients. 2. Both nadolol and carbimazole produced significant reductions in tremor power although nadolol did not cause any change in serum free tri-iodothyronine and free thyroxine concentrations. 3. The results are discussed in terms of the pathogenesis of thyrotoxic tremor and the potential usefulness of tremor in the investigation of adrenergic mechanisms in thyrotoxicosis.

引用

页码：459 / 463

页数：5

共 23 条

[1]

ABILA B, 1984, BRIT J CLIN PHARMACO, V18, pP282

[2]

Chatfield C., 1980, ANAL TIME SERIES INT, V2nd

[3] LOCALIZATION OF TRIIODOTHYRONINE IN NERVE ENDING FRACTIONS OF RAT-BRAIN [J].