EXPRESSION OF BASIC-HELIX-LOOP-HELIX TRANSCRIPTION FACTOR ME2 DURING BRAIN-DEVELOPMENT AND IN THE REGIONS OF NEURONAL PLASTICITY IN THE ADULT BRAIN

被引：38

作者：

SOOSAAR, A

CHIARAMELLO, A

ZUBER, MX

NEUMAN, T

机构：

[1] COLORADO STATE UNIV,DEPT ANAT & NEUROBIOL,FT COLLINS,CO 80523

[2] COLORADO STATE UNIV,DEPT BIOCHEM & MOLEC BIOL,FT COLLINS,CO 80523

[3] ESTONIAN BIOCTR,TARTU,ESTONIA

来源：

MOLECULAR BRAIN RESEARCH | 1994年 / 25卷 / 1-2期

基金：

美国国家科学基金会;

关键词：

BRAIN DEVELOPMENT; HELIX-LOOP-HELIX; GENE EXPRESSION; PLASTICITY; MOUSE DEVELOPMENT;

D O I：

10.1016/0169-328X(94)90297-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We report the isolation of a cDNA encoding the mouse class A bHLH transcription factor ME2 and the analysis of its expression. ME2 is expressed in the cerebral cortex, Purkinje and granule cell layers of the cerebellum, olfactory neuroepithelium, pyramidal cells of hippocampal layers CA1-CA4, and in the granular cells of the dentate gyrus. The specific expression of ME2 during development and in the regions of neuronal plasticity in the adult brain suggest that ME2 may have a regulatory function in developmental processes as well as during neuronal plasticity.

引用

页码：176 / 180

页数：5

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