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GENETIC AND PHARMACOLOGICAL SUPPRESSION OF ONCOGENIC MUTATIONS IN RAS GENES OF YEAST AND HUMANS

被引：550
作者：
SCHAFER, WR
KIM, R
STERNE, R
THORNER, J
KIM, SH
RINE, J
机构：
[1] UNIV CALIF BERKELEY LAWRENCE BERKELEY LAB,BERKELEY,CA 94720
[2] UNIV CALIF BERKELEY,DEPT BIOCHEM,BERKELEY,CA 94720
[3] UNIV CALIF BERKELEY,DEPT CHEM,BERKELEY,CA 94720
来源：
SCIENCE | 1989年 / 245卷 / 4916期
关键词：
D O I：
10.1126/science.2569235
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：379 / 385
页数：7
相关论文
共 74 条
  • [1] MEVINOLIN - A HIGHLY POTENT COMPETITIVE INHIBITOR OF HYDROXYMETHYLGLUTARYL-COENZYME-A REDUCTASE AND A CHOLESTEROL-LOWERING AGENT
    ALBERTS, AW
    CHEN, J
    KURON, G
    HUNT, V
    HUFF, J
    HOFFMAN, C
    ROTHROCK, J
    LOPEZ, M
    JOSHUA, H
    HARRIS, E
    PATCHETT, A
    MONAGHAN, R
    CURRIE, S
    STAPLEY, E
    ALBERSSCHONBERG, G
    HENSENS, O
    HIRSHFIELD, J
    HOOGSTEEN, K
    LIESCH, J
    SPRINGER, J
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (07): : 3957 - 3961
  • [2] MOST HUMAN CARCINOMAS OF THE EXOCRINE PANCREAS CONTAIN MUTANT C-K-RAS GENES
    ALMOGUERA, C
    SHIBATA, D
    FORRESTER, K
    MARTIN, J
    ARNHEIM, N
    PERUCHO, M
    [J]. CELL, 1988, 53 (04) : 549 - 554
  • [3] ANDEREGG RJ, 1988, J BIOL CHEM, V263, P18236
  • [4] [Anonymous], UNPUB
  • [5] RAS GENES
    BARBACID, M
    [J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1987, 56 : 779 - 827
  • [6] STRUCTURAL AND FUNCTIONAL CONSERVATION BETWEEN YEAST AND HUMAN 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASES, THE RATE-LIMITING ENZYME OF STEROL BIOSYNTHESIS
    BASSON, ME
    THORSNESS, M
    FINERMOORE, J
    STROUD, RM
    RINE, J
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1988, 8 (09) : 3797 - 3808
  • [7] SACCHAROMYCES-CEREVISIAE CONTAINS 2 FUNCTIONAL GENES ENCODING 3-HYDROXY-3-METHYLGLUTARYL-COENZYME-A REDUCTASE
    BASSON, ME
    THORSNESS, M
    RINE, J
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (15) : 5563 - 5567
  • [8] BASSON ME, UNPUB
  • [9] RAS PROTEINS CAN INDUCE MEIOSIS IN XENOPUS OOCYTES
    BIRCHMEIER, C
    BROEK, D
    WIGLER, M
    [J]. CELL, 1985, 43 (03) : 615 - 621
  • [10] EXPRESSION OF AN ACTIVATED RAS GENE CAUSES DEVELOPMENTAL ABNORMALITIES IN TRANSGENIC DROSOPHILA-MELANOGASTER
    BISHOP, JG
    CORCES, VG
    [J]. GENES & DEVELOPMENT, 1988, 2 (05) : 567 - 577
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