LONGITUDINAL EXERCISE HEMODYNAMICS IN CHILDREN WITH SICKLE-CELL-ANEMIA

被引：16

作者：

ALPERT, BS ^{[1
]}

DOVER, EV ^{[1
]}

STRONG, WB ^{[1
]}

COVITZ, W ^{[1
]}

机构：

[1] MED COLL GEORGIA, DEPT PEDIAT, PEDIAT CARDIOL SECT, PEDIAT PHYS PERFORMANCE LAB, AUGUSTA, GA 30912 USA

来源：

AMERICAN JOURNAL OF DISEASES OF CHILDREN | 1984年 / 138卷 / 11期

关键词：

D O I：

10.1001/archpedi.1984.02140490021005

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

To define further the natural history and causative factors in exercise-related cardiac dysfunction in children and adolescents with sickle cell anemia (SS), the results of 74 patients'' initial and follow-up exercise tests were studied. The follow-up study was done 1- to 3-yr after the 1st study in 36 children and 4 to 7 yr after initial testing in 38 children. Split-plot analysis of covariance did not show any temporal deterioration in exercise hemodynamic variables. Correlation analysis defined hemoglobin and hematocrit levels as critical determinants of cardiac functional reserve capacity in these patients. Several exercise ECG patterns, formerly considered abnormal in children with SS, are now considered to be variants of normal. Studies are presently in progress that should further define the nature and severity of the cardiac impairment during exercise in children with SS.

引用

页码：1021 / 1024

页数：4

共 15 条

[1] RESPONSES TO ERGOMETER EXERCISE IN A HEALTHY BIRACIAL POPULATION OF CHILDREN [J].