Exploratory laser flash photolysis study of free radical reactions and magnetic field effects in melatonin chemistry

被引：89

作者：

Scaiano, JC

机构：

[1] Department of Chemistry, University of Ottawa, Ottawa, Ontario

来源：

JOURNAL OF PINEAL RESEARCH | 1995年 / 19卷 / 04期

关键词：

EMF; photochemistry; melatonin; micelles; free radicals;

D O I：

10.1111/j.1600-079X.1995.tb00188.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Melatonin is an excellent free radical scavenger, reacting with tert-butoxyl and cumyloxyl radicals with rate constants of 3.4 x 10(7) and 6.7 x 10(7) M(-1)s(-1), respectively. Reaction with benzophenone triplet occurs with a near-diffusion-controlled rate constant of 7.6 x 10(9) M(-1)s(-1) in acetonitrile and probably involves charge transfer. When the radical pair formed by reaction of benzophenone triplet and melatonin is sequestered in a micelle, it is subject to extensive magnetic field effects that can be readily interpreted by the radical pair model.

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页码：189 / 195

页数：7

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