HTLV-II INFECTION IN FLORIDA INDIANS

被引：78

作者：

LEVINE, PH

JACOBSON, S

ELLIOTT, R

CAVALLERO, A

COLCLOUGH, G

DORRY, C

STEPHENSON, C

KNIGGE, RM

DRUMMOND, J

NISHIMURA, M

TAYLOR, ME

WIKTOR, S

SHAW, GM

机构：

[1] NINCDS,BETHESDA,MD 20892

[2] SEMINOLE INDIAN RESERVAT,HOLLYWOOD,FL 33204

[3] RES TRIANGLE INST,ROCKVILLE,MD 20852

[4] UNIV ALABAMA,BIRMINGHAM,AL 35294

[5] PROGRAM RESOURCES INC DYNCORP,FREDERICK,MD 21702

来源：

AIDS RESEARCH AND HUMAN RETROVIRUSES | 1993年 / 9卷 / 02期

关键词：

D O I：

10.1089/aid.1993.9.123

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A significantly increased prevalence of antibodies to human T-cell leukemia virus (HTLV) has been described in several native American populations in the United States and Latin America. Initial virologic studies indicate that HTLV-II is the predominant virus responsible for this antibody pattern. We obtained blood samples from 106 Seminole Indians living on four reservations in Southern Florida. Seropositivity to HTLV-I/II was found in 14 (13.2%) of these individuals. Polymerase chain reaction (PCR) documented HTLV-II and the absence of HTLV-I in 7 of the 9 donors available for follow-up testing of white blood cells. Evaluation of various risk factors excluded blood transfusion or intravenous drug use as an important contributing factor to the HTLV-II seroprevalence rate. These studies support the hypothesis that HTLV-II is endemic in many native American tribes in the Western hemisphere.

引用

页码：123 / 127

页数：5

共 19 条

[1] SPECIES-SPECIFIC DIVERSITY AMONG SIMIAN IMMUNODEFICIENCY VIRUSES FROM AFRICAN-GREEN MONKEYS [J].