TOTAL SYNTHESIS OF THE L-HEXOSES

被引:140
作者
KO, SY [1 ]
LEE, AWM [1 ]
MASAMUNE, S [1 ]
REED, LA [1 ]
SHARPLESS, KB [1 ]
WALKER, FJ [1 ]
机构
[1] MIT,DEPT CHEM,CAMBRIDGE,MA 02139
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
D O I
10.1016/S0040-4020(01)97596-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Enantiomerically pure polyhydroxylated natural products are synthesized by using a reiterative two-carbon extension cycle consisting of four key transformations. The generality and efficiency of this methodology are demonstrated in the total synthesis of all eight L-hexoses. © 1990.
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页码:245 / 264
页数:20
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