ASSOCIATION OF A CHICKEN REPETITIVE ELEMENT WITH THE ENDOGENOUS VIRUS-21 SLOW-FEATHERING LOCUS

被引：17

作者：

LEVIN, I ^{[1
]}

SMITH, EJ ^{[1
]}

机构：

[1] USDA ARS,AVIAN DIS & ONCOL LAB,E LANSING,MI 48823

来源：

POULTRY SCIENCE | 1991年 / 70卷 / 09期

关键词：

INSERTION; DELETION; NUCLEOTIDES; SLOW-FEATHERING LOCUS; ENDOGENOUS VIRUS;

D O I：

10.3382/ps.0701948

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

The DNA sequences of an endogenous virus ev21-cell junction fragment (JFIL-1), and the pristine ev21 unoccupied region were analyzed. Comparisons of 3' proviral sequences of JFIL-1 with comparable regions of ev2, the prototype Rous-associated provirus (RAV-0), revealed minor single-base substitutions in the transmembrane domain of proviral envelope glycoprotein and the long terminal repeat of ev21. In the cell component of the JFIL-1, insertion of a 9-bp direct repeat and deletion of a guanine deoxynucleotide abolished HaeIII and BalI recognition sites that were present in the pristine region. Upstream from the insertion site, a large region was 71 and 75% homologous with dispersed chicken repetitive (CR1) elements associated with vitellogenin and very low density apolipoprotein II genes, respectively. Southern blot hybridizations and comparisons of CR1 motifs such as polypurine tracts, a tandem imperfect octamer, and 6-bp duplications indicated that this sex-linked, CR1 element (CR1ev21) may be the longest member of this family reported thus far.

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页码：1948 / 1956

页数：9

相关论文

共 24 条

[1] ASSOCIATION OF THE SLOW FEATHERING-(K) AND AN ENDOGENOUS VIRAL (EV21) GENE ON THE Z-CHROMOSOME OF CHICKENS [J].

BACON, LD ;

SMITH, E ;

CRITTENDEN, LB ;

HAVENSTEIN, GB .

POULTRY SCIENCE, 1988, 67 (02) :191-197

[2] ACTIVITY OF 2 DIFFERENT SILENCER ELEMENTS OF THE CHICKEN LYSOZYME GENE CAN BE COMPENSATED BY ENHANCER ELEMENTS [J].

BANIAHMAD, A ;

MULLER, M ;

STEINER, C ;

RENKAWITZ, R .

EMBO JOURNAL, 1987, 6 (08) :2297-2303

[3] EXCISION OF THE DBA ECOTROPIC PROVIRUS IN DILUTE COAT-COLOR REVERTANTS OF MICE OCCURS BY HOMOLOGOUS RECOMBINATION INVOLVING THE VIRAL LTRS [J].

COPELAND, NG ;

HUTCHISON, KW ;

JENKINS, NA .

CELL, 1983, 33 (02) :379-387

[4] PRESENCE OF RETROVIRUS REVERSE TRANSCRIPTASE-RELATED GENE-SEQUENCES IN AVIAN CELLS LACKING ENDOGENOUS AVIAN-LEUKOSIS VIRUSES [J].

DUNWIDDIE, C ;

FARAS, AJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (15) :5097-5101

[5] ORGANIZATION, SEQUENCE AND NUCLEASE HYPERSENSITIVITY OF REPETITIVE ELEMENTS FLANKING THE CHICKEN APOVLDLII GENE - EXTENDED SEQUENCE SIMILARITY TO ELEMENTS FLANKING THE CHICKEN VITELLOGENIN GENE [J].

HACHE, RJG ;

DEELEY, RG .

NUCLEIC ACIDS RESEARCH, 1988, 16 (01) :97-113

[6] NUCLEOTIDE-SEQUENCE OF ACCEPTOR SITE AND TERMINI OF INTEGRATED AVIAN ENDOGENOUS PROVIRUS EV1 - INTEGRATION CREATES A 6-BP REPEAT OF HOST DNA [J].

HISHINUMA, F ;

DEBONA, PJ ;

ASTRIN, S ;

SKALKA, AM .

CELL, 1981, 23 (01) :155-164

[7] MOLECULAR ANALYSIS OF ENDOGENOUS VIRUS EV21-SLOW FEATHERING COMPLEX OF CHICKENS .1. CLONING OF PROVIRAL-CELL JUNCTION FRAGMENT AND UNOCCUPIED INTEGRATION SITE [J].

LEVIN, I ;

SMITH, EJ .

POULTRY SCIENCE, 1990, 69 (11) :2017-2026

[8]

Maniatis T., 1982, MOL CLONING

[9] DNA SEQUENCING WITH CHAIN-TERMINATING INHIBITORS [J].

SANGER, F ;

NICKLEN, S ;

COULSON, AR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (12) :5463-5467

[10] NUCLEOTIDE-SEQUENCE OF THE LONG TERMINAL REPEAT AND FLANKING CELLULAR SEQUENCES OF AVIAN ENDOGENOUS RETROVIRUS-EV-2 - VARIATION IN ROUS-ASSOCIATED VIRUS-0 EXPRESSION CANNOT BE EXPLAINED BY DIFFERENCES IN PRIMARY SEQUENCE [J].

SCHOLL, DR ;

KAHN, S ;

MALAVARCA, R ;

ASTRIN, S ;

SKALKA, AM .

JOURNAL OF VIROLOGY, 1983, 45 (02) :868-871