SENSITIVITY OF A DUTCH HEALTH ASSESSMENT QUESTIONNAIRE IN A TRIAL COMPARING HYDROXYCHLOROQUINE VS SULFASALAZINE

被引：61

作者：

VANDERHEIJDE, DMFM

VANRIEL, PLCM

VANDEPUTTE, LBA

机构：

[1] Department of Rheumatology, University Hospital, Nijmegen

来源：

SCANDINAVIAN JOURNAL OF RHEUMATOLOGY | 1990年 / 19卷 / 06期

关键词：

HEALTH ASSESSMENT QUESTIONNAIRE; RHEUMATOID ARTHRITIS; SLOW-ACTING ANTIRHEUMATIC DRUGS; PHYSICAL DISABILITY;

D O I：

10.3109/03009749009097629

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To measure health status in Dutch rheumatoid arthritis patients, we have translated and revised the Health Assessment Questionnaire (HAQ) and added questions about psychosocial status from the Arthritis Impact Measurement Scales (AIMS). The resultant questionnaire turned out to be reproducible and valid. In a double-blind trial comparing Hydroxychloroquine and Sulphasalazine, after 48 weeks the Physical Disability score showed a significant difference in favour of the Sulphasalazine group, reflecting the smaller deterioration in radiographic damage in this group. Thus the Physical Disability part of the questionnaire is sensitive to difference between two slow-acting anti-rheumatic drugs.

引用

页码：407 / 412

页数：6

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