RADIUM TREATMENT FOR HEMANGIOMA IN EARLY-CHILDHOOD - RECONSTRUCTION AND DOSIMETRY OF TREATMENTS, 1920-1959

被引:24
作者
LUNDELL, M
FURST, CJ
HEDLUND, B
HOLM, LE
机构
[1] KAROLINSKA HOSP,RADIUM HEMMET,DEPT GEN ONCOL,S-10401 STOCKHOLM,SWEDEN
[2] KAROLINSKA HOSP,RADIUM HEMMET,DEPT CANC PREVENT,S-10401 STOCKHOLM,SWEDEN
关键词
Children; Hemangioma; Ionizing radiation; Radium dosimetry;
D O I
10.3109/02841869009090049
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Between 1920 and 1959, a total of 14647 children younger than 18 months were treated at Radiumhemmet with ionizing radiation for skin hemangioma. Seventy-two percent of the children were treated with radium needles or tubes, which were put into glass capsules and then applied to the hemangioma. The absorbed doses to different organs have been measured in a tissue equivalent phantom, representing a 6-month-old child. For a standard treatment of 8 Gy to the hemangioma the mean absorbed doses to the brain, eye lens, parotid gland, thyroid, breast anlage and gonads from 28 different treatment areas were 0.03-0.2 Gy. The mean absorbed dose to the organs in younger (<2 months) and older (14-18 months) children were up to 50% higher (0.04-0.1 Gy) and 33% lower (0.02-0.06 Gy) respectively, than for a 6-month-old child. The uncertainty in organ absorbed doses for each patient depended mostly on the estimation of the distance between the applicator and the site. ©1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
引用
收藏
页码:551 / 556
页数:6
相关论文
共 22 条
[1]  
ENGSTROM L, 1960, LAKARTIDNINGEN, V57, P1750
[2]  
FINCH SC, 1984, PROGR CANCER RES THE, V26, P37
[3]  
FURST CJ, 1987, ACTA ONCOL, V26, P33
[4]  
FURST CJ, 1989, ACTA ONCOL, V28, P789
[5]   CANCER INCIDENCE AFTER RADIOTHERAPY FOR SKIN HEMANGIOMA - A RETROSPECTIVE COHORT STUDY IN SWEDEN [J].
FURST, CJ ;
LUNDELL, M ;
HOLM, LE ;
SILFVERSWARD, C .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1988, 80 (17) :1387-1392
[6]  
FURST CJ, 1990, IN PRESS ACTA ONCOL
[7]   FOLLOW-UP-STUDY OF PATIENTS TREATED BY X-RAY EPILATION FOR TINEA CAPITIS - ESTIMATION OF DOSE TO THYROID AND PITUITARY-GLANDS AND OTHER STRUCTURES OF HEAD AND NECK [J].
HARLEY, NH ;
ALBERT, RE ;
SHORE, RE ;
PASTERNACK, BS .
PHYSICS IN MEDICINE AND BIOLOGY, 1976, 21 (04) :631-642
[8]   NEOPLASMS IN PERSONS TREATED WITH X-RAYS IN INFANCY - 4TH SURVEY IN 20 YEARS [J].
HEMPELMANN, LH ;
HALL, WJ ;
PHILLIPS, M ;
COOPER, RA ;
AMES, WR .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1975, 55 (03) :519-530
[9]   RISK OF EXTRATHYROID TUMORS FOLLOWING RADIATION TREATMENT IN INFANCY FOR THYMIC ENLARGEMENT [J].
HILDRETH, NG ;
SHORE, RE ;
HEMPELMANN, LH ;
ROSENSTEIN, M .
RADIATION RESEARCH, 1985, 102 (03) :378-391
[10]  
Karlberg P, 1976, ACTA PAEDIATR SC S, V258, P7