SINGLE-BREATH NITRIC-OXIDE MEASUREMENTS IN ASTHMATIC-PATIENTS AND SMOKERS

被引：418

作者：

PERSSON, MG

ZETTERSTROM, O

AGRENIUS, V

IHRE, E

GUSTAFSSON, LE

机构：

[1] KAROLINSKA INST,DEPT PHYSIOL,S-17177 STOCKHOLM,SWEDEN

[2] KAROLINSKA INST,INST ENVIRONM SCI,S-10401 STOCKHOLM 60,SWEDEN

[3] KAROLINSKA HOSP,DEPT THORAC MED,S-10401 STOCKHOLM 60,SWEDEN

来源：

LANCET | 1994年 / 343卷 / 8890期

关键词：

D O I：

10.1016/S0140-6736(94)90935-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Exhaled nitric oxide (NO) concentrations were measured in asthmatic outpatients and in non-smoking and smoking healthy controls. In single exhalations, NO showed a peak suggestive of airway origin in both controls and asthmatic patients. The peak NO concentration was higher in asthmatic patients and lower in smokers than in non-smoking controls (p<0.05). The findings support a role for NO in the host defence response in asthma and suggest that NO measurements can discriminate between different types of lung disorders.

引用

页码：146 / 147

页数：2

共 9 条

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