INHIBITION OF DIHYDROFOLATE-REDUCTASE - EFFECT OF REDUCED NICOTINAMIDE ADENINE-DINUCLEOTIDE PHOSPHATE ON THE SELECTIVITY AND AFFINITY OF DIAMINOBENZYLPYRIMIDINES

被引：105

作者：

BACCANARI, DP ^{[1
]}

DALUGE, S ^{[1
]}

KING, RW ^{[1
]}

机构：

[1] NATL INST MED RES,LONDON NW7 1AA,ENGLAND

来源：

BIOCHEMISTRY | 1982年 / 21卷 / 20期

关键词：

D O I：

10.1021/bi00263a034

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：5068 / 5075

页数：8

共 39 条

[1] METHOXY GROUP NONPLANARITY IN OMICRON-DIMETHOXYBENZENES - SIMPLE PREDICTIVE MODELS FOR CONFORMATIONS AND ROTATIONAL BARRIERS IN ALKOXYAROMATICS [J].

ANDERSON, GM ;

KOLLMAN, PA ;

DOMELSMITH, LN ;

HOUK, KN .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1979, 101 (09) :2344-2352

[2]

BACCANARI DP, 1981, J BIOL CHEM, V256, P1738

[3] DIHYDROFOLATE-REDUCTASE HYSTERESIS AND ITS EFFECT ON INHIBITOR BINDING ANALYSES [J].

BACCANARI, DP ;

JOYNER, SS .

BIOCHEMISTRY, 1981, 20 (07) :1710-1716

[4] ESCHERICHIA-COLI DIHYDROFOLATE-REDUCTASE - ISOLATION AND CHARACTERIZATION OF 2 ISOZYMES [J].

BACCANARI, DP ;

AVERETT, D ;

BRIGGS, C ;

BURCHALL, J .

BIOCHEMISTRY, 1977, 16 (16) :3566-3572

[5]

BACCANARI DP, 1981, FED PROC, V40, P1748

[6] THE BINDING OF TRIMETHOPRIM TO BACTERIAL DIHYDROFOLATE-REDUCTASE [J].

BAKER, DJ ;

BEDDELL, CR ;

CHAMPNESS, JN ;

GOODFORD, PJ ;

NORRINGTON, FEA ;

SMITH, DR ;

STAMMERS, DK .

FEBS LETTERS, 1981, 126 (01) :49-52

[7] H-1 NUCLEAR MAGNETIC-RESONANCE STUDIES OF LACTOBACILLUS-CASEI DIHYDROFOLATE-REDUCTASE - EFFECTS OF SUBSTRATE AND INHIBITOR BINDING ON HISTIDINE RESIDUES [J].

BIRDSALL, B ;

GRIFFITHS, DV ;

ROBERTS, GCK ;

FEENEY, J ;

BURGEN, A .

PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1977, 196 (1124) :251-265

[8] BINDING OF COENZYME ANALOGS TO LACTOBACILLUS-CASEI DIHYDROFOLATE-REDUCTASE - BINARY AND TERNARY COMPLEXES [J].

BIRDSALL, B ;

BURGEN, ASV ;

ROBERTS, GCK .

BIOCHEMISTRY, 1980, 19 (16) :3723-3731

[9]

Blakley R. L., 1969, FRONT BIOL

[10]

BURCHALL JJ, 1974, TOPICS INFECTIOUS DI, V1, P285

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