YEAST ARTIFICIAL CHROMOSOMES - TOOLS FOR MAPPING AND ANALYSIS OF COMPLEX GENOMES

被引：81

作者：

SCHLESSINGER, D ^{[1
]}

机构：

[1] WASHINGTON UNIV,SCH MED,CTR GENET MED,ST LOUIS,MO 63110

来源：

TRENDS IN GENETICS | 1990年 / 6卷 / 08期

关键词：

D O I：

10.1016/0168-9525(90)90207-M

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Libraries of yeast artificial chromosomes (YACs) are representative of complex genomes, and typical YACs contain single fragments of DNA that are up to a megabase or more in size, are stable during growth, and are faithful to genomic DNA. Such YACs may permit (1) the use of complete gene units for a number of research and medical purposes; and (2) the assembly of chromosome-sized contigs in a single map that unifies genetic and physical data. © 1990.

引用

页码：248 / &

共 43 条

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