NONRESPONSE BIAS IN STUDIES OF DIABETIC COMPLICATIONS - THE ROCHESTER DIABETIC NEUROPATHY STUDY

被引:61
作者
MELTON, LJ
DYCK, PJ
KARNES, JL
OBRIEN, PC
SERVICE, FJ
机构
[1] MAYO CLIN & MAYO FDN, CTR PERIPHERAL NERVE, ROCHESTER, MN 55905 USA
[2] MAYO CLIN & MAYO FDN, DIV ENDOCRINOL METAB & INTERNAL MED, ROCHESTER, MN 55905 USA
关键词
DIABETES MELLITUS; EPIDEMIOLOGY; NONRESPONSE BIAS; CARDIOVASCULAR DISEASE; NEUROPATHY;
D O I
10.1016/0895-4356(93)90148-T
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Non-response can bias studies of disease conditions but its influence has rarely been evaluated due to limitations of available data on the non-respondents. Because of a detailed medical record review for eligibility, we were able to compare clinical as well as demographic characteristics of respondents and non-respondents in a population-based study of diabetic complications among Rochester, Minnesota residents. Non-respondents were older, less well educated, more likely to be widowed and more often retired. They were much more likely to have cardiovascular disease at baseline, but the prevalence of retinopathy, nephropathy and diabetic neuropathy was similar for respondents and non-respondents, who were also comparable with regard to type of diabetes and diabetic therapy. While these findings indicate that data from the Rochester Diabetic Neuropathy Study can probably be generalized to diabetic residents generally, they reemphasize the potential for non-response bias in epidemiologic studies of clinical conditions, especially cardiovascular disease.
引用
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页码:341 / 348
页数:8
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