LONG-TERM EFFECTS OF GASTROCYSTOPLASTY IN RATS

被引：46

作者：

KLEE, LW

HOOVER, DM

MITCHELL, ME

RINK, RC

机构：

[1] INDIANA UNIV, MED CTR, UNIV HOSP A112, DEPT UROL, INDIANAPOLIS, IN 46202 USA

[2] ELI LILLY INT CORP, LILLY RES LAB, INDIANAPOLIS, IN 46285 USA

[3] UNIV WASHINGTON, CHILDRENS HOSP, SEATTLE, WA 98195 USA

来源：

JOURNAL OF UROLOGY | 1990年 / 144卷 / 05期

关键词：

D O I：

10.1016/S0022-5347(17)39720-3

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Twenty prepubescent rats underwent microsurgical gastrocystoplasty by a technique which is described. An equal number of control rats had their bladders opened and closed. Rats were sacrificed at 16 to 18 months postoperatively. There were no differences in final weight, serum electrolytes, or renal function between the two groups. Prominent histopathologic changes of the bladder occurred in the gastrocystoplasty group. These changes included papillomas present in five of the 15 rats surviving long term. No significant changes occurred in the bladders of the control group of rats. Possible etiologies and the significance of the rats. Possible etiologies and the significance of the gastrocystoplasty related lesions are discussed.

引用

页码：1283 / 1287

页数：5

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