ENANTIOSELECTIVE REACTION OF DIETHYLZINC WITH ARENECARBALDEHYDES IN THE PRESENCE OF EPHEDRINE DERIVATIVES

被引：35

作者：

CHALONER, PA

LANGADIANOU, E

PERERA, SAR

机构：

[1] School of Chemistry and Molecular Sciences, University of Sussex, Falmer

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 11期

关键词：

D O I：

10.1039/p19910002731

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of diethylzinc with a range of arenecarbaldehydes has been catalysed by N-alkyl ephedrines to give 1-arylpropan-1-ols with good to excellent optical yields. The enantioselectivity of the reaction was substantially improved by the use of a 4 molar excess of the organozinc reagent.

引用

页码：2731 / 2735

页数：5

共 21 条

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