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TGF-BETA ACCELERATED THE OSTEOGENIC DIFFERENTIATION OF BONE-MARROW CELLS INDUCED BY COLLAGEN MATRIX
被引：21
作者：
MIZUNO, M
KUBOKI, Y
机构：
[1] Hokkaido Univ, Sch Dent, Dept Biochem, Sapporo, Hokkaido
关键词：
D O I：
10.1006/bbrc.1995.1923
中图分类号：
Q5 [生物化学];
Q7 [分子生物学];
学科分类号：
071010 ;
081704 ;
摘要：
Bone marrow cells have multipotency for differentiation. Recently we found that type I collagen matrix induced the osteogenic differentiation of bone marrow cells. In this study we showed that TGF-beta enhanced the effect of collagen matrix on bone marrow cells and accelerated the osteogenic differentiation. These results imply that TGF-beta might play a crucial role in the osteogenic differentiation of bone marrow cells during embryogenesis and the repair of bone. (C) 1995 Academic Press, Inc.
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页码：1091 / 1098
页数：8
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