CELLULOSE XANTHIDE (CELLX) AS AN ENCAPSULATING MATRIX .1. COMPARISON WITH STARCH XANTHIDE (STX) ON SWELLING AND RELEASE PROPERTIES

被引：5

作者：

BOTE, AN ^{[1
]}

NADKARNI, VM ^{[1
]}

RAJAGOPALAN, N ^{[1
]}

机构：

[1] NATL CHEM LAB,DIV POLYMER CHEM,POONA 411008,INDIA

来源：

JOURNAL OF CONTROLLED RELEASE | 1993年 / 27卷 / 03期

关键词：

CELLULOSE XANTHIDE; STARCH XANTHIDE; CONTROLLED RELEASE; SWELLING CONTROL; SINGLE PARTICLE RELEASE;

D O I：

10.1016/0168-3659(93)90152-U

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The efficacy of cellulose, converted through viscose intermediate to crosslinked cellulose xanthide, as an encapsulant is compared with starch xanthide which has already been reported [ 1-4 ] to be an effective matrix for encapsulation. Factors such as crystallinity, extent of crosslinking and percentage loading and their influence on equilibrium water uptake and release property are examined. The release kinetics conform to 'swelling controlled release systems' and the data are interpreted in terms of the generalised equation M(t)/M(infinity)=kt(n). The bulk release studies of the polydisperse system could not indicate the exact release mechanism. Single particle release studies indicate that both the systems could conform to case II or zero order release governed by matrix relaxation controlled release.

引用

页码：207 / 217

页数：11

共 18 条

[1] WATER-SWELLING BEHAVIOR OF AN ETHYLENE-VINYL ALCOHOL CO-POLYMER IN THE PRESENCE OF SORBED SODIUM-CHLORIDE [J].