BIOCONVERSION OF RHODODENDROL BY ACER NIKOENSE

被引：15

作者：

FUJITA, T

HATAMOTO, H

IWASAKI, T

TAKAFUJI, S

机构：

[1] Snow Brand Milk Products, Co., Ltd., Technical Research Institute, Saitama

来源：

PHYTOCHEMISTRY | 1995年 / 39卷 / 05期

关键词：

ACER NIKOENSE; ACERACEAE; CALLUS CULTURE; SUSPENSION CULTURE; RHODODENDROL; BIOCONVERSION;

D O I：

10.1016/0031-9422(95)00102-D

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Callus derived from Acer nikoense tissue contained the same compounds as the parent plants, but (+)-rhododendrol, which has hepatoprotective activity, was not detected in the methanol extract of the callus. Cells in suspension culture converted (RS)-rhododendrol into (RS)-rhododendrol 2-O-beta-D-glucopyranoside and (R)-rhododendrol 2-O-beta-D-xylopyranosyl-(1 --> 6)-beta-D-glucopyranoside. This is the first time that the latter compound has been isolated from a natural source.

引用

页码：1085 / 1089

页数：5

共 11 条

[1]

ASADA Y, 1990, CHEM PHARM BULL, V38, P142, DOI 10.1248/cpb.38.142

[2] STEREOSPECIFIC SYNTHESIS AND ABSOLUTE-CONFIGURATION OF (+)-RHODODENDROL [J].

DAS, B ;

RAO, SP ;

SRINIVAS, KVNS ;

YADAV, JS .

PHYTOCHEMISTRY, 1993, 33 (06) :1529-1530

[3]

FUJITA T, 1992, Patent No. 475587

[4] STUDIES ON PLANT-TISSUE CULTURE .59. BIOTRANSFORMATION OF 2-PHENYLPROPIONIC ACID IN ROOT CULTURE OF PANAX-GINSENG [J].

FURUYA, T ;

USHIYAMA, M ;

ASADA, Y ;

YOSHIKAWA, T .

PHYTOCHEMISTRY, 1989, 28 (02) :483-487

[5] STUDIES ON CONSTITUENTS OF ACERACEAE PLANTS .1. CONSTITUENTS IN LEAVES AND STEM BARK OF ACER-NIKOENSE-MAXIM [J].

INOUE, T ;

ISHIDATE, Y ;

FUJITA, M ;

KUBO, M ;

FUKUSHIMA, M ;

NAGAI, M .

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1978, 98 (01) :41-46

[6] STEREOCHEMISTRY OF C-METHYLATION IN BIOSYNTHESIS OF RHODODENDRIN IN ALNUS AND BETULA [J].

KLISCHIES, M ;

ZENK, MH .

PHYTOCHEMISTRY, 1978, 17 (08) :1281-1284

[7]

KUBO M, 1983, CHEM PHARM BULL, V31, P1917

[8] A REVISED MEDIUM FOR RAPID GROWTH AND BIO ASSAYS WITH TOBACCO TISSUE CULTURES [J].

MURASHIGE, T ;

SKOOG, F .

PHYSIOLOGIA PLANTARUM, 1962, 15 (03) :473-497

[9] PROTECTIVE EFFECTS OF THE FRACTIONS EXTRACTED FROM THE CALLUS OF ACER-NIKOENSE MAXIM ON ALPHA-NAPHTHYLISOTHIOCYANATE INDUCED LIVER-INJURY [J].

NAKAMURA, H ;

KUMAZAWA, N ;

OHTA, S ;

FUJITA, T ;

IWASAKI, T ;

SHINODA, M .

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1992, 112 (02) :115-123

[10] PROTECTIVE EFFECTS OF THE FRACTIONS EXTRACTED FROM THE CALLUS OF ACER-NIKOENSE MAXIM ON CARBON-TETRACHLORIDE INDUCED LIVER-INJURY [J].

NAKAMURA, H ;

KUMAZAWA, N ;

OHTA, S ;

FUJITA, T ;

IWASAKI, T ;

SHINODA, M .

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1991, 111 (10) :585-591

← 1 2 →