CONSTITUENTS OF TROPICAL MEDICINAL-PLANTS .63. SYNTHESIS OF 2-METHOXYONYCHINE ALKALOIDS - STRUCTURE REVISION OF OXYLOPIDINE

被引:6
作者
ACHENBACH, H
SCHWINN, A
机构
[1] Institut für Pharmazie und Lebensmittelchemie, Universität Erlangen, Erlangen, D-91052
关键词
D O I
10.1002/ardp.19943271202
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Condensation of beta-aminocinnamic acid esters with 3-chloro-2-methoxycrotonaldehyde opened an easy access to 2-phenyl-5-merhoxy-4-methylnicotinic acid esters which were cyclized by polyphosphoric acid to yield the corresponding 2-methoxyonychines. By this method a number of 2-methoxy-substituted onychines were prepared for the first time, i.a. oxylopidine, the structure of which has to be revised.
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页码:755 / 762
页数:8
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