A NOVEL PITUITARY TRANSCRIPTION FACTOR IS PRODUCED BY ALTERNATIVE SPLICING OF THE HUMAN GHF-1/PIT-1 GENE

被引：27

作者：

DELHASE, M

VILA, V

HOOGHEPETERS, EL

CASTRILLO, JL

机构：

[1] UNIV AUTONOMA MADRID,CSIC,CTR BIOL MOLEC SEVERO OCHOA,E-28049 MADRID,SPAIN

[2] FREE UNIV BRUSSELS,SCH MED,DEPT PHARMACOL,B-1090 BRUSSELS,BELGIUM

来源：

GENE | 1995年 / 155卷 / 02期

关键词：

RECOMBINANT DNA; TISSUE-SPECIFIC GENE EXPRESSION; POU TRANSCRIPTION FACTOR; GROWTH HORMONE;

D O I：

10.1016/0378-1119(94)00757-J

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

An alternative splice acceptor site in intron 1 of the human GHF-1/PIT-1 gene was sequenced. The use of this splice site is responsible for a 78-bp in-frame insertion upstream from exon 2 and leads to the hGHF-2/PIT-2 cDNA detected in normal human pituitary.

引用

收藏

页码：273 / 275

页数：3

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