Cytosolic cysteine in redox signaling

被引：16

作者：

Carmen Lopez-Martin, M.

Romero, Luis C.

Gotor, Cecilia ^{[1
]}

机构：

[1] Univ Seville, Avda Americo Vespucio 49, Seville 41092, Spain

来源：

PLANT SIGNALING & BEHAVIOR | 2008年 / 3卷 / 10期

关键词：

Arabidopsis; O-acetylserine(thiol) lyase; cysteine biosynthesis; redox regulation;

D O I：

10.4161/psb.3.10.6289

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cysteine biosynthesis in plants takes place in the three cellular compartments with autonomous protein biosynthesis machinery: cytosol, plastids and mitochondria. This sulfur-containing molecule is synthesized sequentially in these compartments by two enzymatic families, the serine acetyltransferases and the O-acetylserine( thiol) lyases. Each family consists of several isoforms that differ in subcellular localization and abundance. Why so many isoforms are required in plant cell for cysteine biosynthesis has remained unknown to date. The characterization of gene-specific knockout mutants has started to address this question. In our recent work, we have performed a detailed analysis of the Arabidopsis oas-a1 null mutant and showed that the antioxidant capacity of the cytosol is compromised, highlighting the contribution of cytosolic Cys in redox signaling.

引用

页码：880 / 881

页数：2

共 8 条

[1] Evidence for a direct link between glutathione biosynthesis and stress fefense gene expression in Arabidopsis [J].