A H-1-NMR STUDY OF THE ROLE OF THE GLUTAMATE MOIETY IN THE BINDING OF METHOTREXATE TO LACTOBACILLUS-CASEI DIHYDROFOLATE-REDUCTASE

被引：25

作者：

ANTONJUK, DJ ^{[1
]}

BIRDSALL, B ^{[1
]}

CHEUNG, HTA ^{[1
]}

CLORE, GM ^{[1
]}

FEENEY, J ^{[1
]}

GRONENBORN, A ^{[1
]}

ROBERTS, GCK ^{[1
]}

TRAN, TQ ^{[1
]}

机构：

[1] NATL INST MED RES,DIV MOLEC PHARMACOL,LONDON NW7 1AA,ENGLAND

来源：

关键词：

D O I：

10.1111/j.1476-5381.1984.tb10080.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：309 / 315

页数：7

共 27 条

[1] ANTONJUK DJ, 1984, J CHEM SOC
[2] Bertino J. R. [Ed.]., 1971, Ann NY Acad Sci, V186, P1
[3] H-1 NUCLEAR MAGNETIC-RESONANCE STUDIES OF LACTOBACILLUS-CASEI DIHYDROFOLATE-REDUCTASE - EFFECTS OF SUBSTRATE AND INHIBITOR BINDING ON HISTIDINE RESIDUES
BIRDSALL, B
GRIFFITHS, DV
ROBERTS, GCK
FEENEY, J
BURGEN, A
[J]. PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1977, 196 (1124): : 251 - 265
[4] BINDING OF COENZYME ANALOGS TO LACTOBACILLUS-CASEI DIHYDROFOLATE-REDUCTASE - BINARY AND TERNARY COMPLEXES
BIRDSALL, B
BURGEN, ASV
ROBERTS, GCK
[J]. BIOCHEMISTRY, 1980, 19 (16) : 3723 - 3731
[5] Blakley R. L., 1969, FRONT BIOL
[6] BOLIN JT, 1982, J BIOL CHEM, V257, P13650
[7] METHOTREXATE ANALOGS .3. SYNTHESIS AND BIOLOGICAL PROPERTIES OF SOME SIDE-CHAIN ALTERED ANALOGS
CHAYKOVSKY, M
ROSOWSKY, A
PAPATHANASOPOULOS, N
CHEN, KKN
MODEST, EJ
KISLIUK, RL
GAUMONT, Y
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (11) : 1212 - 1216
[8] LARGE-SCALE PURIFICATION AND CHARACTERIZATION OF DIHYDROFOLATE-REDUCTASE FROM A METHOTREXATE-RESISTANT STRAIN OF LACTOBACILLUS-CASEI
DANN, JG
OSTLER, G
BJUR, RA
KING, RW
SCUDDER, P
TURNER, PC
ROBERTS, GCK
BURGEN, ASV
HARDING, NGL
[J]. BIOCHEMICAL JOURNAL, 1976, 157 (03) : 559 - 571
[9] DOMIN BA, 1982, MOL PHARMACOL, V21, P231
[10] GRONENBORN A, 1981, BIOCHEMISTRY-US, V20, P1712