RESPONSE TO TOREMIFENE (FC-1157A) THERAPY IN TAMOXIFEN FAILED PATIENTS WITH BREAST-CANCER - PRELIMINARY COMMUNICATION

被引：14

作者：

EBBS, SR ^{[1
]}

ROBERTS, J ^{[1
]}

BAUM, M ^{[1
]}

机构：

[1] KINGS COLL HOSP,DEPT SURG,LONDON SE5 9NU,ENGLAND

来源：

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY | 1990年 / 36卷 / 03期

关键词：

D O I：

10.1016/0022-4731(90)90016-L

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nine patients with measurable lesions of locally advanced or recurrent breast cancer have been treated with toremifene 200 mg daily. A response rate of 33% [complete remission (CR) + partial remission (PR)] or 78% [CR + PR + no change (NC)] has been achieved so far. As all our patients had previously relapsed on anti-oestrogen therapy (tamoxifen), we postulate that our response rate was achieved by a direct oncolytic effect. © 1990.

引用

页码：239 / 239

页数：1